Currently, IBM Mote Runner runs exclusively on Crossbow Iris motes. The Iris mote comprises an Atmel ATmega1281 processor, an Atmel RF230 radio controller for 2.4 GHz communication in accordance with to IEEE 802.15.4, 128 KB of program flash memory, and 8 KB of RAM.

Crossbow offers various sensor boards for the Iris, of which Mote Runner currently supports the MTS420 partially, namely its dual-axis accelerometer and the relative humidity / temperature sensor.