Computational systems biology

Developing predictive models for precision medicine

Open positions

PhD opportunity: COSMIC, COmbating disorders of adaptive immunity with Systems MedICine

Ref. 2017-15

A PhD research position is available at the IBM Research – Zurich Laboratory, as a part of the H2020 COSMIC consortium, focused on understanding disorders of the adaptive immune system.

Background: EU countries face large health challenges to combat chronic diseases. Recently, systems medicine has emerged as a promising discipline to accelerate the translation of basic research into applications for improved diagnostics and personalized treatment. Its power arises from the integration of laboratory and computational approaches crossing research disciplines and sectors to solve clinical questions.

Approach: COSMIC will focus on B-cell neoplasia and rheumatoid arthritis, prototypical diseases originating from abnormal functioning of immune cells, often resulting in similar antigen specificities. The successful candidate will develop new algorithms to understand the molecular mechanisms of these diseases, and to identify strategies for optimal personalized patient treatment.

Starting date: 1 June 2018.


  • Strong background in computer science, mathematics, physics or similar.
  • Working knowledge of C or C++.
  • Working knowledge of Matlab, R or equivalent.
  • Comfortable knowledge of statistics and mathematical modeling.

In addition, the following experience would be helpful, but not essential:

  • Experience in machine learning, deep learning, big data analysis, and high performance computing.
  • Experience in systems biology or systems medicine.


IBM is committed to diversity at the workplace. With us you will find an open, multicultural environment. Excellent flexible working arrangements enable both women and men to strike the desired balance between their professional development and their personal lives.

How to apply

Interested candidates should apply through the COSMIC website under “Vacancies”. Please mention there that you wish to be considered for the position at the IBM Research – Zurich Lab.
Application materials can also be sent to .